The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression

Emily L.L. SIN; Ho-Ling LIU; Shwu-Hua LEE; Chih-Mao HUANG; Yau-Yau WAI; Yao-Liang CHEN; Che Hin Chetwyn CHAN; Chemin LIN; Tatia M.C. LEE

doi:10.1002/gps.4831

The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression

Emily L.L. SIN
, Ho-Ling LIU
, Shwu-Hua LEE
, Chih-Mao HUANG
, Yau-Yau WAI
, Yao-Liang CHEN
, Che Hin Chetwyn CHAN
, Chemin LIN
, Tatia M.C. LEE

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Research output: Contribution to journal › Articles › peer-review

21 Citations (Scopus)

Abstract

Objective: Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence.

Methods: Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories.

Results: This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. Copyright © 2017 The Authors.

Original language	English
Pages (from-to)	606-612
Journal	International Journal of Geriatric Psychiatry
Volume	33
Issue number	4
Early online date	Dec 2017
DOIs	https://doi.org/10.1002/gps.4831
Publication status	Published - Apr 2018

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Late‐life depression
MRI
Perceived loneliness
Voxel‐based morphometry

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10.1002/gps.4831Licence: CC BY-NC-ND

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published version

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title = "The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression",

abstract = "Objective: Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence. Methods: Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories. Results: This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. Copyright {\textcopyright} 2017 The Authors.",

author = "SIN, \{Emily L.L.\} and Ho-Ling LIU and Shwu-Hua LEE and Chih-Mao HUANG and Yau-Yau WAI and Yao-Liang CHEN and CHAN, \{Che Hin Chetwyn\} and Chemin LIN and LEE, \{Tatia M.C.\}",

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AU - SIN, Emily L.L.

AU - LIU, Ho-Ling

AU - LEE, Shwu-Hua

AU - HUANG, Chih-Mao

AU - WAI, Yau-Yau

AU - CHEN, Yao-Liang

AU - CHAN, Che Hin Chetwyn

AU - LIN, Chemin

AU - LEE, Tatia M.C.

PY - 2018/4

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N2 - Objective: Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence. Methods: Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories. Results: This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. Copyright © 2017 The Authors.

AB - Objective: Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence. Methods: Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories. Results: This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. Copyright © 2017 The Authors.

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SN - 0885-6230

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EP - 612

JO - International Journal of Geriatric Psychiatry

JF - International Journal of Geriatric Psychiatry

IS - 4

ER -

The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression

Abstract

UN SDGs

Keywords

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