The power of dissociation: Development of displacement assays for chemosensing and latent catalytic systems

Cheuk Fai Stephen CHOW, Anxun ZHENG, Min HUANG, Chang SHEN

Research output: Contribution to journalArticle

Abstract

Disassembly is an essential process in supramolecular chemistry, and its exploitation has resulted in the development of four different displacement assays: (a) indicator-displacement assay (IDA), (b) indicator/catalyst-displacement assay (ICDA), (c) catalytic/indicator-displacement assay (CIDA), and (d) catalyst-displacement assay (CDA). These consist of bimetallic donor–acceptor ensembles (BmDAEs), which incorporate various metallic signal transducers, receptors, inhibitors, catalysts, and pre-catalysts. Applications thereof include pollutant degradation, signal amplification, chemosensing detection, and latent catalysis. This review discusses the use of bimetallic supramolecular systems for the development of catalysts, chemosensors, and chemodosimeters. Copyright © 2020 Royal Society of Chemistry.
Original languageEnglish
JournalMaterials Chemistry Frontiers
Early online date26 Feb 2020
DOIs
Publication statusE-pub ahead of print - 26 Feb 2020

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Citation

Chow, C.-F., Zheng, A., Huang, M., & Shen, C. (2020). The power of dissociation: Development of displacement assays for chemosensing and latent catalytic systems. Materials Chemistry Frontiers. Advance online publication. doi: 10.1039/C9QM00639G