Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands

Quan TANG, Wen-Xiu NI, Chi Fai LEUNG, Wai-Lun MAN, Kenneth King Kwan LAU, Yimin LIANG, Yun Wah LAM, Wai Yeung WONG, Shie Ming PENG, Gui Jian LIU, Tai-Chu LAU

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Abstract

A series of osmium(VI) nitrido complexes supported by quinolinolato ligands have been prepared and they exhibit promising in vitro anti-cancer activities. These results establish that Osᵛᴵ≡N is a potentially versatile and promising platform for the design of a variety of high-valent anti-cancer drugs. Copyright © 2013 The Royal Society of Chemistry.
Original languageEnglish
Pages (from-to)9980-9982
JournalChemical Communications
Volume49
Issue number85
Early online dateAug 2013
DOIs
Publication statusPublished - Nov 2013

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Citation

Tang, Q., Ni, W.-X., Leung, C.-F., Man, W.-L., Lau, K. K.-K., Liang, Y., et al. (2013). Synthesis and antitumor activity of a series of osmium(VI) nitrido complexes bearing quinolinolato ligands. Chemical Communications, 49(85), 9980-9982.