Stuttered swallowing: Electric stimulation of the right insula interferes with water swallowing. A case report

Peter SÖRÖS, Faisal AL-OTAIBI, Wai Ho Savio WONG, J. Kevin SHOEMAKER, Seyed M. MIRSATTARI, Vladimir HACHINSKI, Ruth E. MARTIN

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Abstract

Background: Various functional resonance imaging, magnetoencephalographic and lesion studies suggest the involvement of the insular cortex in the control of swallowing. However, the exact location of insular activation during swallowing and its functional significance remain unclear.
Case presentation: Invasive electroencephalographic monitoring was performed in a 24-year-old man with medically intractable stereotyped nocturnal hypermotor seizures due to a ganglioglioma. During stimulation of the right inferior posterior insular cortex with depth electrodes the patient spontaneously reported a perception of a “stutter in swallowing”. Stimulation of the inferior posterior insular cortex at highest intensity (4 mA) was also associated with irregular and delayed swallows. Swallowing was not impaired during stimulation of the superior posterior insular cortex, regardless of stimulation intensity.
Conclusions: These results indicate that the right inferior posterior insular cortex is involved in the neural circuitry underlying the control of swallowing. Copyright © 2011 Sörös et al; licensee BioMed Central Ltd.
Original languageEnglish
Article number20
JournalBMC Neurology
Volume11
DOIs
Publication statusPublished - 2011

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Deglutition
Cerebral Cortex
Electric Stimulation
Water
Ganglioglioma
Swallows
Electrodes
Seizures

Citation

Sörös, P., Al-Otaibi, F., Wong, S. W. H., Shoemaker, J. K., Mirsattari, S. M., Hachinski, V., & Martin R. E. (2011). Stuttered swallowing: Electric stimulation of the right insula interferes with water swallowing. A case report. BMC Neurology, 11. Retrieved from https://doi.org/10.1186/1471-2377-11-20

Keywords

  • Insular cortex
  • Anterior insula
  • Intractable epilepsy
  • Ganglioglioma
  • Depth electrode