Stability of Montreal Cognitive Assessment in individuals with mild cognitive impairment: Potential influence of practice effect

Lauren K.S. LEI, Bess Y.H. LAM, Daniel W.L. LAI, Xue BAI, Jessica LI, Zhi ZOU, Che Hin Chetwyn CHAN

Research output: Contribution to journalArticlespeer-review

Abstract

Background: The Montreal Cognitive Assessment (MoCA) is a standard test for screening and monitoring cognitive functions. Objective: This study explored the two-year changes in MoCA scores in older adults. Methods: Fifty-seven participants with mild cognitive impairment (MCI) and 87 participants with normal cognition completed the baseline and two-year follow-up assessments. Apart from MoCA, tests on visuospatial judgment, memory, and motor-related executive function were administered. Results: The results identified three MCI subgroups based on the differential changes in MoCA scores. They were the consistently low, consistently high, and low-to-high between-time performances. These heterogeneous test performances are on contrary to the significant deteriorations in executive function and finger dexterity across all subgroups. Repeated exposure to MoCA tests during the follow-up period was found to be a plausible indicator of the MCI subgroup categorization. Conclusion: Findings raise concerns over adopting brief clinical instrument for repeated testing, such as MoCA, for monitoring MCI conditions among older adults. Copyright © 2022 IOS Press. All rights reserved.

Original languageEnglish
Pages (from-to)1401-1412
JournalJournal of Alzheimer's Disease
Volume87
Issue number3
DOIs
Publication statusPublished - May 2022

Citation

Lei, L. K. S., Lam, B. Y. H., Lai, D. W. L., Bai, X., Li, J., Zou, Z., & Chan, C. C. H. (2022). Stability of Montreal Cognitive Assessment in individuals with mild cognitive impairment: Potential influence of practice effect. Journal of Alzheimer's Disease, 87(3), 1401-1412. doi: 10.3233/JAD-220003

Keywords

  • Aging
  • Mild cognitive impairment
  • Montreal cognitive assessment

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