Single vs. two steroid injections for carpal tunnel syndrome: A randomised clinical trial

S. M. WONG, A. C. F. HUI, Sing Kai LO, J. H. CHIU, W. F. POON, L. WONG

Research output: Contribution to journalArticlespeer-review

30 Citations (Scopus)

Abstract

We investigated the efficacy of a single vs. double steroid injections in the treatment of carpal tunnel syndrome (CTS) in a randomised double-blind controlled trial. Patients with idiopathic CTS were randomised into (i) one group receiving a baseline methylprednisolone acetate injection plus a saline injection 8 weeks later and (ii) a second group receiving methylprednisolone acetate injection at baseline and at 8 weeks. The primary outcome was the Global Symptom Score (GSS). Forty patients were recruited. By 40 weeks, the mean GSS improved from 25.6 to 14.1 in the single-injection group whereas from 26.7 to 12.6 in the reinjection group, but there was no significant difference in GSS between the two groups (p = 0.26). There were also no significant differences in terms of electrophysiological and functional outcomes. The results suggest that an additional steroid injection confers no added benefit to a single injection in terms of symptom relief. Copyright © 2005 Blackwell Publishing Ltd.
Original languageEnglish
Pages (from-to)1417-1421
JournalInternational Journal of Clinical Practice
Volume59
Issue number12
DOIs
Publication statusPublished - Dec 2005

Citation

Wong, S. M., Hui, A. C. F., Lo, S. K., Chiu, J. H., Poon, W. F., & Wong, L. (2005). Single vs. two steroid injections for carpal tunnel syndrome: A randomised clinical trial. International Journal of Clinical Practice, 59(12), 1417-1421. doi: 10.1111/j.1368-5031.2005.00696.x

Keywords

  • Carpal tunnel syndrome
  • Steroid injection
  • Randomised controlled trial

Fingerprint

Dive into the research topics of 'Single vs. two steroid injections for carpal tunnel syndrome: A randomised clinical trial'. Together they form a unique fingerprint.