Reliability of radiographic intervertebral disc height measurement for in vivo rat-tail model

Alon LAI, Hung Kay Daniel CHOW, W. S. SIU, Andrew D. HOLMES, F. H. TANG

Research output: Contribution to journalArticles

14 Citations (Scopus)

Abstract

Quantification of changes in intervertebral disc height is critical for studying intervertebral disc degeneration. Reliability of disc height measurement is therefore especially important for in vivo studies using animal models of disc degeneration. In this study, the effects of image intensity and percentage of disc width used for disc height measurement from radiographic images were evaluated in a rat-tail model. Radiographs were taken for 10 Sprague-Dawley rats using a standardized protocol. Average disc heights of the caudal 8-9 discs were determined using original and intensity adjusted images with different percentages of disc width. The average disc height was found to be significantly affected by both the image intensity and the percentage of disc width measured. A higher reliability was found in the measurement for image with adjusted intensity and using smaller disc width. Image intensity is suggested to be controlled and the disc width should be taken into account in quantifying the disc height. Copyright © 2006 IPEM. Published by Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)814-819
JournalMedical Engineering and Physics
Volume29
Issue number7
DOIs
Publication statusPublished - Sep 2007

Citation

Lai, A., Chow, D. H. K., Siu, W. S., Holmes, A. D., & Tang, F. H. (2007). Reliability of radiographic intervertebral disc height measurement for in vivo rat-tail model. Medical Engineering & Physics, 29(7), 814-819. doi: 10.1016/j.medengphy.2006.08.013

Keywords

  • Intervertebral disc
  • Disc height
  • Degeneration
  • Rat model
  • Radiological image

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