Recent advances in nanomaterial-based human breath analytical technology for clinical diagnosis and the way forward

Ehsanul KABIR, Nadeem RAZA, Vanish KUMAR, Jagpreet SINGH, Yiu Fai TSANG, Dong Kwon LIM, Jan Edward SZULEJKO, Ki-Hyun KIM

Research output: Contribution to journalArticles

4 Citations (Scopus)

Abstract

For the putative diagnosis of various health disorders, the use of nanomaterial (NM)-based sensors for the detection of biomarkers in breath samples has become an emerging research field. In this work, we offer a systemic review on NM-based sensing of key breath biomarkers (mainly volatile organic compounds [VOCs]) based on the up-to-date survey of available techniques and relevant data. Also, we provide a basis for thorough evaluation to specifically address the technological gaps and bewildering factors of this emerging technique. Nonetheless, the use of NM-based detection approaches is still unsatisfactory and immature (e.g., real-time point-of-care applications) due to a number of demerits (e.g., extremely long rise and slew times). To ideally resolve the remaining obstacles in this research field and to avoid a "false dawn" scenario, NM-based breath sensing techniques should be dealt as a priority subject for future research and development. Copyright © 2019 Elsevier Inc.
Original languageEnglish
Pages (from-to)3020-3057
JournalChem
Volume5
Issue number12
Early online dateSep 2019
DOIs
Publication statusPublished - Dec 2019

Citation

Kabir, E., Raza, N., Kumar, V., Singh, J., Tsang, Y. F., Lim, D. K., . . . Kim, K.-H. (2019). Recent advances in nanomaterial-based human breath analytical technology for clinical diagnosis and the way forward. Chem, 5(12), 3020-3057. doi: 10.1016/j.chempr.2019.08.004

Keywords

  • Breath analysis
  • Nanomaterial
  • Sensor
  • Volatile organic compound

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