Oxygen saturation and heart rate variations as predictors of intradialytic hypotension

Vincent King Yu CHAN, Lawrence Wing Chi CHAN, Hung Kay Daniel CHOW

Research output: Contribution to journalArticle

1 Citation (Scopus)


Intradialytic hypotension (IDH) occurring during hemodialysis (HD) may cause severe complications and can be life-threatening. IDH is a common symptom in patients with end stage renal disease undergoing HD. Currently, no effective predictive models for IDH exist. This study analyzed data on variations in oxygen saturation (SaO₂) and heart rate (HR) in 68 patients during their HD sessions by using sequence alignment and Boolean algebra. Three classifiers derived from SaO₂ and HR variation data were developed as predictors for predetermining IDH occurrence within 30 minutes. The accuracy of these classifiers in predicting IDH occurrence was approximately 80%. SaO₂ and HR variations can potentially be used as predictors for developing an alarm system for detecting IDH occurrence. Copyright © 2018 American Nephrology Nurses Association.
Original languageEnglish
Pages (from-to)53-60
JournalNephrology Nursing Journal
Issue number1
Publication statusPublished - Jan 2018


Heart Rate
Renal Dialysis
Sequence Alignment
Chronic Kidney Failure


Chan, V. K. Y., Chan, L. W. C., & Chow, D. H. K. (2018). Oxygen saturation and heart rate variations as predictors of intradialytic hypotension. Nephrology Nursing Journal, 45(1), 53-60.


  • Intradialytic hypotension
  • Saturation of oxygen
  • Heart rate
  • Sequence alignment