Mutagenicity and genotoxicity of Hong Kong soils contaminated by polycyclic aromatic hydrocarbons and dioxins/furans

Yu Bon MAN, Ka Lai CHOW, Yuan KANG, Ming Hung WONG

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13 Citations (Scopus)

Abstract

The aim of this study was to evaluate mutagenicity and genotoxicity of soils from 12 different land use types such as electronic waste dismantling workshop, open burning site and car dismantling workshop (CDW), based on soil concentrations of polycyclic aromatic hydrocarbons (PAHs), and polychlorinated dibenzo- p-dioxins/polychlorinated dibenzofurans (PCDD/Fs). Soils of CDW contained the sum of 10 PAHs level (94392 μg/kg) exceeded The New Dutch List (Dutch Intervention Value (40000 μg/kg)), dominated by high molecular PAHs (99.6%) and benzo(a)pyrene (82.6%), indicating its potential carcinogenic risks. In addition, Ames test and SOS Chromotest further manifested that soil of CDW had a significantly higher mutagenic potency (MP) of 13.8 and 7.43 on both strains of TA98 and TA100 with S9 mix, respectively, and a relatively higher genotoxicity with S9 mix (SOS inducing potency = 1.16), amongst the 12 different soil types. BaP TEQ PAHs in soils were significantly correlated with MP of TA98, with and without S9 mix (r= 0.858 and r= 0.976 at p< 0.01); MP of TA100 with and without S9 mix (r= 0.666 at p< 0.05 and r= 0.819 at p< 0.01); and SOSIP of Escherichia coli PQ 37 with S9 mix (r= 0.693 at p< 0.05), accordingly. Soils of CDW possessed a higher carcinogenic risk (mutagenicity and genotoxicity), based on PAHs concentrations. Bioremediation is recommended to treat the contaminated soils. Copyright © 2013 Elsevier B.V. All rights reserved.

Original languageEnglish
Pages (from-to)47-56
JournalMutation Research - Genetic Toxicology and Environmental Mutagenesis
Volume752
Issue number1-2
Early online date04 Feb 2013
DOIs
Publication statusPublished - 15 Apr 2013

Citation

Man, Y. B., Chow, K. L., Kang, Y., & Wong, M. H. (2013). Mutagenicity and genotoxicity of Hong Kong soils contaminated by polycyclic aromatic hydrocarbons and dioxins/furans. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 752(1-2), 47-56. doi: 10.1016/j.mrgentox.2013.01.004

Keywords

  • Mutagenicity
  • Genotoxicity
  • Ames test
  • SOS Chromotest
  • PAHs
  • PCDD/Fs

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