Low coverage of influenza vaccination among Chinese children aged 12-23 months: Prevalence and associated factors

Joseph T. F. LAU, Sau Man Catalina NG, Anise M. S. WU, Yee Ling MA, Mason M. C. LAU

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1 Citation (Scopus)


This study aimed to investigate prevalence and associated factors of influenza vaccination (IV) among children aged 12–23 months. Our cross-sectional survey interviewed 489 parents of children aged 12–23 months anonymously at twelve maternal and child health centers in Hong Kong. Results showed that only 11.5% of the children had ever received IV (64.3% being subsidized). Adjusted for the child's age, significant factors of the children's IV included parental knowledge about governmental policy/recommendation (Adjusted odds ratio [AOR] = 2.64, 95%CI = 1.09,6.40), knowledge about annual IV requirement (AOR = 2.30, 95%CI = 1.21,4.38), perceived safety-related barrier (AOR≥0.14, 95%CI = 0.06,0.33), cue to action (AOR = 7.79, 95%CI = 3.45,17.58), and subjective norm (AOR = 4.59, 95%CI = 2.34,9.00). IV prevalence of children aged 12–23 months remained low despite a subsidization scheme. The higher IV prevalence of older children reported by other studies suggested that parents postponed action. Promotion campaigns should shift emphases from cost reduction and mass media approaches to dissemination of knowledge about IV policy and safety, enhancement of health professionals' advice, and creation of supportive subjective norm. Copyright © 2018 Lau et al.
Original languageEnglish
Article numbere0205561
JournalPLoS One
Issue number10
Publication statusPublished - Oct 2018


Human Influenza
Cost reduction
odds ratio
Odds Ratio
Maternal-Child Health Centers
Mass Media
mass media
Age Factors
Hong Kong
health care workers
cross-sectional studies
Cross-Sectional Studies
Costs and Cost Analysis


Lau, J. T. F., Ng, C. S. M., Wu, A. M. S., Ma, Y. L., & Lau, M. M. C. (2018). Low coverage of influenza vaccination among Chinese children aged 12-23 months: Prevalence and associated factors. PloS One, 13(10). Retrieved from https://doi.org/10.1371/journal.pone.0205561