Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results

Ching-Yeh HSIUNG, Margie A. HUNT, Ellen D. YORKE, Chen-Shou CHUI, Jason HU, Jian-Ping XIONG, Clifton C. LING, Sing Kai LO, Chong-Jong WANG, Eng-Yen HUANG, Howard I. AMOLS

Research output: Contribution to journalArticlespeer-review

11 Citations (Scopus)

Abstract

The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry. Copyright © 2005 Elsevier Ireland Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)53-57
JournalRadiotherapy and Oncology
Volume77
Issue number1
DOIs
Publication statusPublished - Oct 2005

Citation

Hsiung, C.-Y., Hunt, M. A., Yorke, E. D., Chui, C.-S., Hu, J., Xiong, J.-P., . . . Amols, H. I. (2005). Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results. Radiotherapy and Oncology, 77(1), 53-57. doi: 10.1016/j.radonc.2005.04.017

Keywords

  • Nasopharyngeal carcinoma
  • Intensity-modulated radiotherapy
  • Inverse planning
  • Optimization
  • Anatomic factor

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