The current study demonstrates that the large increase in normal tissue penalty often degrades target dose uniformity without a concomitant large improvement in normal tissue dose, especially in anatomically unfavorable patients. The excessively large normal tissue penalties do not improve treatment plans for patients having unfavorable geometry. Copyright © 2005 Elsevier Ireland Ltd. All rights reserved.
CitationHsiung, C.-Y., Hunt, M. A., Yorke, E. D., Chui, C.-S., Hu, J., Xiong, J.-P., . . . Amols, H. I. (2005). Intensity-modulated radiotherapy as the boost or salvage treatment of nasopharyngeal carcinoma: The appropriate parameters in the inverse planning and the effect of patient's anatomic factors on the planning results. Radiotherapy and Oncology, 77(1), 53-57. doi: 10.1016/j.radonc.2005.04.017
- Nasopharyngeal carcinoma
- Intensity-modulated radiotherapy
- Inverse planning
- Anatomic factor