Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates

Hui-zhen WANG, Minnie M. L. WONG, Desmond O'TOOLE, Mandy M. H. MAK, Shiu Sun Rudolf WU, Richard Y. C. KONG

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21 Citations (Scopus)

Abstract

In this study we identified a putative virulence-associated DNA methyltransferase (MTase) gene carried on a novel 22.79-kb pathogenicity island-like element (VPAI) in V. parahaemolyticus. The V. parahaemolyticus MTase gene was shown by PCR to be prevalent (>98%) in pandemic thermostable direct hemolysin gene-positive isolates, which suggests that VPAI may confer unique virulence traits to pandemic strains of V. parahaemolyticus. Copyright © 2006 American Society for Microbiology. All Rights Reserved.

Original languageEnglish
Pages (from-to)4455-4460
JournalApplied and Environmental Microbiology
Volume72
Issue number6
DOIs
Publication statusPublished - Jun 2006

Citation

Wang, H.-Z., Wong, M. M. L., O'Toole, D., Mak, M. M. H., Wu, R. S. S., & Kong, R. Y. C. (2006). Identification of a DNA methyltransferase gene carried on a pathogenicity island-like element (VPAI) in Vibrio parahaemolyticus and its prevalence among clinical and environmental isolates. Applied and Environmental Microbiology, 72(6), 4455-4460. doi: 10.1128/AEM.02095-05

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