Effects of the modified Huanglian Jiedu decoction on the disease resistance in grey mullet (Mugil cephalus) to Lactococcus garvieae

Wai Ming CHOI, Chun Leung LAM, Wing Yin MO, Zhang CHENG, Nai Ki MAK, Zhao-Xiang BIAN, Ming Hung WONG

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Lactococcosis is prevalent on grey mullet (Mugil cephalus) in Hong Kong aquaculture resulting in serious economic loss. A compound formulation of Traditional Chinese Medicines (TCM) (modified Huanglian Jiedu decoction (HLJDD)) comprising Rhizoma coptidis, Radix scutellaria, Cortex phellodendri, Fructus gardeniae, Fructus forsythiae and Flos lonicerae japonicae (in a ratio of 3:2:2:3:3:5) were applied as feed supplements to deal with the disease. The Nitroblue tetrazolium activity in blood, bactericidal activity and total immunoglobulin in plasma were significantly enhanced after feeding 1% of this TCM for 28 days. The disease resistances to Lactococcus garvieae in 1% and 2% TCM feeding groups were significantly enhanced. In the in vitro study, the modified HLJDD also activated the plasma bactericidal activities (p < 0.01). Based on this study, 1% modified HLJDD feeding for 28 days may be an optimal dose to preventL. garvieae infection and could be used in aquaculture industries. Copyright © 2014 Elsevier Ltd.
Original languageEnglish
Pages (from-to)816-823
JournalMarine Pollution Bulletin
Volume85
Issue number2
Early online dateMay 2014
DOIs
Publication statusPublished - 2014

Citation

Choi, W. M., Lam, C. L., Mo, W. Y., Cheng, Z., Mak, N. K., Bian, Z. X., Wong, M. H. (2014). Effects of the modified Huanglian Jiedu decoction on the disease resistance in grey mullet (Mugil cephalus) to Lactococcus garvieae. Marine Pollution Bulletin, 85(2), 816-823.

Keywords

  • Traditional Chinese Medicine
  • Lactococcus garvieae
  • Grey mullet
  • Bactericidal activity
  • Aquaculture

Fingerprint Dive into the research topics of 'Effects of the modified Huanglian Jiedu decoction on the disease resistance in grey mullet (Mugil cephalus) to Lactococcus garvieae'. Together they form a unique fingerprint.