Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma)

Meng YAN, Maggie Y.L. MAK, Jinping CHENG, Jing LI, Jia Rui GU, Priscilla T.Y. LEUNG, Paul K.S. LAM

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12 Citations (Scopus)

Abstract

Ciguatoxins are natural compounds produced by benthic dinoflagellates Gambierdiscus and Fukuyoa spp., which cause fish intoxication by ciguatera fish poisoning. This study aimed to assess the dietary exposure effects of ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma). Fish which ingested >1.16 pg·day⁻¹ for 21 days exhibited abnormal behaviors including diarrhea, abnormal swimming, loss of appetite and decreased egg production. After 7-day exposure to P-CTX-1 at a dose of 1.93 pg·day⁻¹, significant gender-specific differences in reproductive performance and decreased hatching rate of the offspring were observed. Chemical analysis of P-CTX-1 showed that the P-CTX-1 accumulation rates were 24.1 ± 1.4% in female fish and 9.9 ± 0.4% in male fish, and 0.05 pg·egg⁻¹ was detected. The results illustrate that dietary exposure to P-CTX-1 affected the reproductive performance and survival of offspring, and caused bioaccumulation and maternal transfer of P-CTX-1 in marine medaka. Copyright © 2020 Elsevier Ltd.
Original languageEnglish
Article number110837
JournalMarine Pollution Bulletin
Volume152
DOIs
Publication statusPublished - Mar 2020

Citation

Yan, M., Mak, M. Y. L., Cheng, J., Li, J., Gu, J. R., Leung, P. T. Y., & Lam, P. K. S. (2020). Effects of dietary exposure to ciguatoxin P-CTX-1 on the reproductive performance in marine medaka (Oryzias melastigma). Marine Pollution Bulletin, 152. Retrieved from https://doi.org/10.1016/j.marpolbul.2019.110837

Keywords

  • Gambierdiscus
  • Ciguatoxin
  • Bio-encapsulation
  • Reproduction
  • Oryzias melastigma
  • Maternal transfer

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