Concentrations and congener profiles of polybrominated diphenyl ethers (PBDEs) in blood plasma from Hong Kong: Implications for sources and exposure route

Hong-Sheng WANG, Guan-Min JIANG, Zhuo-Jia CHEN, Jun DU, Yu Bon MAN, John P. GLESY, Chris K.C. WONG, Ming Hung WONG

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Abstract

There was limited information about bioaccumulation of polybrominated diphenyl ethers (PBDEs) in humans of the general population of Hong Kong. Therefore, the present study was conducted to determine concentrations and congener profiles of PBDEs in blood plasma from Hong Kong, evaluate their sources and correlations with other organobrominated compounds, and investigate exposure routes from fish and dust. Concentrations of ∑PBDE22 ranged from 0.56 to 92 ng g−1, lipid weight (lw), with a median of 5.4 ng g−1. BDE-47 was the dominant congener, accounting for 26% of ∑PBDE22. Concentrations of PBDE congeners in market fish were significantly (r2 = 0.89, p < 0.001) correlated with plasma. Positive but no significant correlations were observed, between concentrations of PBDE congeners in indoor dust from workplaces (r2 = 0.46, p = 0.081) and homes (r2 = 0.49, p = 0.10), with concentrations of PBDE in human blood plasma. The results indicated that dietary exposure, particularly consumption of fish, is a major pathway through which people in Hong Kong are exposed to PBDEs. Furthermore, our data revealed a spatial distribution and terrestrial source of BDE-28 for local people. Results of the present study, which was the first systematic study to investigate concentrations of PBDEs in blood of Hong Kong people, provides useful information to which future measurements can be compared. Copyright © 2013 Elsevier B.V. Published by Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)253-259
JournalJournal of Hazardous Materials
Volume261
Early online dateJul 2013
DOIs
Publication statusPublished - Oct 2013

Fingerprint

Halogenated Diphenyl Ethers
PBDE
Hong Kong
Ethers
Blood
blood
Plasmas
plasma
Fish
Fishes
Dust
fish
dust
Bioaccumulation
exposure
workplace
Workplace
Lipids
Spatial distribution
bioaccumulation

Citation

Wang, H.-S., Jiang, G.-M., Chen, Z.-J., Du, J., Man, Y.-B., Giesy, J. P., . . . Wong, M.-H. (2013). Concentrations and congener profiles of polybrominated diphenyl ethers (PBDEs) in blood plasma from Hong Kong: Implications for sources and exposure route. Journal of Hazardous Materials, 261, 253-259. doi: 10.1016/j.jhazmat.2013.07.033

Keywords

  • PBDEs
  • Plasma
  • Fish
  • Dust
  • Bioaccumulation