Biodegradation and enzymatic responses in the marine diatom Skeletonema costatum upon exposure to 2,4-dichlorophenol

Shao YANG, Shiu Sun Rudolf WU, Richard Y. C. KONG

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54 Citations (Scopus)

Abstract

The biodegradation and responses of selected detoxification and antioxidant enzymes in the marine diatom, Skeletonema costatum, upon exposure to sublethal concentrations of 2,4-dichlorophenol (2,4-DCP) were investigated. Results show that 2,4-DCP was readily metabolised, but bioaccumulation and adsorption were negligible. Glutathione S-transferase, ascorbate peroxidase and superoxide dismutase activities were increased markedly after exposure to 2,4-DCP for 96 h, while no appreciable change in peroxidase activity was observed. The addition of exogeneous glutathione to diatom culture enhanced the degradation of 2,4-DCP, and promoted diatom growth. The inhibition of glutathione synthesis enhanced the toxicity of 2,4-DCP. These results suggest that glutathione conjugation was one of the principal mechanisms involved in the degradation of 2,4-DCP in this diatom. Copyright © 2002 Elsevier Science B.V. All rights reserved.

Original languageEnglish
Pages (from-to)191-200
JournalAquatic Toxicology
Volume59
Issue number3-4
DOIs
Publication statusPublished - 24 Sep 2002

Citation

Yang, S., Wu, R. S. S., & Kong, R. Y. C. (2002). Biodegradation and enzymatic responses in the marine diatom Skeletonema costatum upon exposure to 2,4-dichlorophenol. Aquatic Toxicology, 59(3-4), 191-200. doi: 10.1016/S0166-445X(01)00252-1

Keywords

  • 2,4-Dichlorophenol
  • Degradation
  • Diatom
  • Detoxification
  • Enzyme

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