Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment

Yuan KANG, Yi YIN, Yu Bon MAN, Laisheng LI, Qiuyun ZHANG, Lixuan ZENG, Jiwen LUO, Ming Hung WONG

Research output: Contribution to journalArticles

16 Citations (Scopus)

Abstract

Human exposure to bioaccessible PCBs via indoor dust is limited around the world. In the present study, the workplace dust sample from commercial office, hospital, secondary school, shopping mall, electronic factory and manufacturing plant were collected from Hong Kong for PCBs analyses. Total PCBs concentrations ranged from 46.8 to 249 ng g−1, with a median of 107 ng g−1. Manufacturing plant showed the highest concentration among all of sampling sites. PCB 77 was found as the dominant congeners. The bioaccessibility of PCBs in small intestinal juice ranging from 8.3% to 26.0% was significantly higher than that in gastric condition, ranging from 4.8% to 12.4%. In addition, significant negative correlations (p < 0.05) were observed between KOW and bioaccessibility for all workplace dust samples. Risk assessment indicated that the averaged daily dose of dioxin-like PCBs via non-dietary intake of workplace dust, considering the bioaccessibility of PCBs, were much lower than the TDI of dioxins (2.3 pg WHO-TEQ kg bw−1 d−1) established by Joint FAO/WHO Expert Committee on Food Additives. Copyright © 2013 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)924-930
JournalChemosphere
Volume93
Issue number6
Early online dateJul 2013
DOIs
Publication statusPublished - Oct 2013

Citation

Kang, Y., Yin, Y., Man, Y., Li, L., Zhang, Q., Zeng, L., . . . Wong, M. H. (2013). Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment. Chemosphere, 93(6), 924-930. doi: 10.1016/j.chemosphere.2013.05.057

Keywords

  • PCBs
  • Workplace dust
  • Bioaccessibility
  • Risk Assessment

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