BiliCheck transcutaneous bilirubinometer: A screening tool for neonatal jaundice in the Chinese population

E. Y. W. HO, S. Y. R. LEE, C. B. CHOW, Wai Yee Joanne CHUNG

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19 Citations (Scopus)

Abstract

Objective. To verify the usefulness of the BiliCheck transcutaneous bilirubin meter as a screening device for neonatal jaundice in a Chinese population compared with the Minolta bilirubin meter. 

Design. A prospective correlation study that compared transcutaneous bilirubin measurements with serum bilirubin levels. 

Setting. Obstetric ward and a neonatal unit of a regional hospital in Hong Kong. 

Patients. Neonates with gestation above 32 weeks with neonatal jaundice who were admitted between April 2001 and February 2002. 

Main outcome measures. Transcutaneous measurements of serum bilirubin obtained from the forehead and the sternum with two instruments: BiliCheck and Minolta Airshields JM 102. 

Results. A total of 77 term and six near-term babies (gestation, 32-37 weeks) were recruited. The mean age at the time of data collection was 3.96 days (range, 2-9 days). The correlations between serum bilirubin and transcutaneous bilirubin measurements of the two devices at the two sites were high, with a coefficient of 0.718 (95% confidence interval, 0.610-0.800; n=100) for forehead measurements, and 0.814 (95% confidence interval, 0.740-0.870; n=99) for sternum using the Minolta Airshields JM 102; and a coefficient of 0.757 (95% confidence interval, 0.657-0.827; n=98) for forehead measurements, and 0.794 (95% confidence interval, 0.700-0.862; n=92) for sternum using the BiliCheck. For BiliCheck, a cut-off point of 250 μmol/L at the forehead and 260 μmol/L at the sternum had a specificity of 61.9% and 70.0%, respectively with a sensitivity of 100% for the detection of serum bilirubin concentrations of 250 μmol/L or higher. This level is commonly used as the level for initiation of treatment such as phototherapy. 

Conclusion. BiliCheck is a useful screening tool for neonatal jaundice in the Chinese population and is comparable with the Minolta Airshields JM 102. 

目的:比較BiliCheck經皮膽紅素計和Minolta膽紅素計在篩檢華人新生兒黃疽的有效程度。

設計:比較經皮膽紅素測量和血清膽紅素的關係研究。

安排:香港一所地區醫院產科病房和兒科部門。

患者:2001年4月至 2002年2月期間接收患有黃疸的新生兒。

主要結果來測量:使用BiliCheck和Minolta Airshield JM 102兩種儀器在患者前額和胸部經皮量度膽紅素。

結果:研究期間共接收77位滿月嬰兒和6位接近滿月的嬰兒(妊娠期為32-37星期),收集資料時嬰兒的平均年齡為3.96天(介乎2-9天)。分別在兩個部位用兩種儀器經皮量度的膽紅素值、與血清膽紅素有很大的相關性。用Minolta Airshield JM 102在前額量度的相關係數為0.718(95% 可信區間為0.610-0.800,n=100),在胸骨量度的相關係數為0.814(95%可信區間為0.740-0.870,n=99)。用BiliCheck在前額量度的相關係數為0.757(95%可信區間為0.657-0.827,n=98),在胸骨量度的相關係數為0.794(95%可信區間為0.700-0.862,n=92)。以BiliCheck量度前額的切斷點達250 μmol/L時,特異性為 61.9%,量度胸骨的切斷點是260 μmol/L時,特異性則為70.0%,偵測250 μmol/L或以上的血清膽紅素濃度的敏感性則達100%,光照療法等治療措施經常以此作為治療的起始水平。

結論:BiliCheck經皮膽紅素計是一種篩檢華人新生兒黃疽的有效儀器,效果與Minolta Airshield JM 102相若。Copyright © 2006 Hong Kong Academy of Medicine and the Hong Kong Medical Association.

Original languageEnglish
Pages (from-to)99-102
JournalHong Kong Medical Journal
Volume12
Issue number2
Publication statusPublished - Apr 2006

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Citation

Ho, E. Y. W., Lee, S. Y. R., Chow, C. B., & Chung, J. W. Y. (2006). BiliCheck transcutaneous bilirubinometer: A screening tool for neonatal jaundice in the Chinese population. Hong Kong Medical Journal, 12(2), 99-102.

Keywords

  • Bilirubin/blood
  • Comparative study
  • Infant, newborn
  • Jaundice, neonatal
  • Neonatal screening
  • Alt. title: BiliCheck經皮膽紅素計:一種篩檢華人新生兒黃疸的工具
  • 膽紅素/血液
  • 比較研究
  • 嬰兒,新生
  • 黃疸,新生兒
  • 新生兒篩檢