Arsenic speciation in total contents and bioaccessible fractions in atmospheric particles related to human intakes

Minjuan HUANG, Xunwen CHEN, Yinge ZHAO, Chuen Yu CHAN, Wei WANG, Xuemei WANG, Ming Hung WONG

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18 Citations (Scopus)

Abstract

Speciation of inorganic trivalent arsenicals (iAsIII), inorganic pentavalent arsenicals (iAsV), monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA) in total arsenic (As) content and its bioaccessible fractions contained in road dust, household air-conditioning (AC) filter dust and PM2.5 was investigated. Inorganic As, especially iAsV, was observed as the dominant species. Physiologically based extraction test (PBET), an in-vitro gastrointestinal method, was used to estimate the oral As bioaccessibility in coarse particles and the species present in the oral bioaccessible fraction. A composite lung simulating serum was used to mimic the pulmonary condition to extract the respiratory bioaccessible As and its species in PM2.5. Reduction of iAsV to iAsIII occurred in both in-vitro gastrointestinal and lung simulating extraction models. The inorganic As species was the exclusive species for absorption through ingestion and inhalation of atmospheric particles, which was an important exposure route to inorganic As, in addition to drinking water and food consumption. Copyright © 2014 Elsevier Ltd.
Original languageEnglish
Pages (from-to)37-44
JournalEnvironmental Pollution
Volume188
Early online dateFeb 2014
DOIs
Publication statusPublished - 2014

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Arsenic
Arsenicals
Dust
Lung
Air Filters
Cacodylic Acid
Air Conditioning
Acids
Air conditioning
Potable water
Drinking Water
Inhalation
Drinking
Eating
Food
Composite materials
Serum

Citation

Huang, M., Chen, X., Zhao, Y., Chan, C. Y., Wang, W., Wang, X., et al. (2014). Arsenic speciation in total contents and bioaccessible fractions in atmospheric particles related to human intakes. Environmental Pollution, 188, 37-44.

Keywords

  • As speciation
  • HPLC–ICP-MS
  • Bioaccessibility
  • Daily intakes of inorganic As