Adequacy of using a three-item questionnaire to determine zygosity in Chinese young twins

Suk Han Connie HO, Mo ZHENG, Bonnie Wing-Yin CHOW, Wai Lap Simpson WONG, Cadmon K. P. LIM, Miu Yee Mary WAYE

Research output: Contribution to journalArticles

Abstract

The present study examined the adequacy of a three-item parent questionnaire in determining the zygosity of young Chinese twins and whether there was any association between parent response accuracy and some demographic variables. The sample consisted of 334 pairs of same-sex Chinese twins aged from 3 to 11 years. Three scoring methods, namely the summed score, logistic regression, and decision tree, were employed to evaluate parent response accuracy of twin zygosity based on single nucleotide polymorphism (SNP) information. The results showed that all three methods achieved high level of accuracy ranging from 91 to 93 % which was comparable to the accuracy rates in previous Chinese twin studies. Correlation results also showed that the higher the parents’ education level or the family income was, the more likely parents were able to tell correctly that their twins are identical or fraternal. The present findings confirmed the validity of using a three-item parent questionnaire to determine twin zygosity in a Chinese school-aged twin sample. Copyright © 2016 Springer Science+Business Media New York.
Original languageEnglish
Pages (from-to)244-254
JournalBehavior Genetics
Volume47
Issue number2
Early online dateNov 2016
DOIs
Publication statusPublished - Mar 2017

Citation

Ho, C. S.-H., Zheng, M., Chow, B. W.-Y., Wong, S. W. L., Lim, C. K. P., & Waye, M. M. Y. (2017). Adequacy of using a three-item questionnaire to determine zygosity in Chinese young twins. Behavior Genetics, 47(2), 244-254.

Keywords

  • Zygosity
  • Chinese
  • Young twins
  • Parent questionnaire

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