A pilot study on health risk assessment based on body loadings of PCBs of lactating mothers at Taizhou, China, the world's major site for recycling transformers

Yu Bon MAN, Ka Lai CHOW, Guan Hua Xing, Kit Yan Janet CHAN, Sheng Chun WU, Ming Hung WONG

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9 Citations (Scopus)

Abstract

Our early study reported an extraordinarily high Estimated Daily Intake (EDI) of PCBs of lactating mothers from Taizhou, Zhejiang Province, China (based on a food consumption survey and food basket analysis). The EDI well exceeded the intake limit stipulated by FAO/WHO 70 pg TEQ/kg body weight (bw)/month. The present pilot study provided further information on PCBs body burden in lactating mothers of Taizhou. The total PCBs detected in human milk, placenta and hair samples of these lactating mothers were 363 ng/g lipid, 224 ng/g lipid, and 386 ng/g dry wt. Respectively, three times higher than those samples collected from the reference site (Lin'an). Compared with the previous reported values in the 3rd WHO coordinated study, Taizhou topped the list of 32 countries/regions with regards to WHO-PCB-TEQ values of milk samples, which could be attributed to the relatively higher level of PCB-126 derived from electronic waste. In addition, the corresponding EDI of PCBs of Taizhou mothers (12.9 pg WHO-PCB-TEQ/kg bw/day) and infants (438 pg WHO-PCB-TEQ/kg) were derived from individual congener levels in human milk. The results were also higher than the tolerable daily intakes recommended by WHO (1–4 pg WHO-TEQ/kg bw/day) by 3 and 110 times, for mothers and infants, respectively. A more intensive epidemiological study on the potential health effects of e-waste recycling activities affecting both workers and residents seems to be of top priority, based on findings of this pilot study. Copyright © 2017 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)364-371
JournalEnvironmental Pollution
Volume227
Early online dateMay 2017
DOIs
Publication statusPublished - Aug 2017

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Health risks
Polychlorinated Biphenyls
Recycling
Polychlorinated biphenyls
Risk assessment
China
Mothers
Health
3,4,5,3',4'-pentachlorobiphenyl
Body Weight
Human Milk
Electronic Waste
Lipids
Food Analysis
Body Burden
No-Observed-Adverse-Effect Level
Hair
Placenta
Epidemiologic Studies
Milk

Citation

Man, Y. B., Chow, K. L., Xing, G. H., Chan, J. K. Y., Wu, S. C., & Wong, M. H. (2017). A pilot study on health risk assessment based on body loadings of PCBs of lactating mothers at Taizhou, China, the world's major site for recycling transformers. Environmental Pollution, 227, 364-371.

Keywords

  • Electronic waste
  • Human milk
  • Placenta
  • Hair
  • Health effects