A photoresponsive surface molecularly imprinted polymer shell for determination of trace griseofulvin in milk

Yue-Hong YANG, Lan-Tao LIU, Mei-Jun CHEN, Song LIU, Cheng-Bin GONG, Yu-Bo WEI, Cheuk Fai Stephen CHOW, Qian TANG

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

A new photoresponsive surface molecularly imprinted polymer shell (PMIPS) was developed for determination of trace griseofulvin from milk. The PMIPS was prepared by surface imprinting technique using poly(styrene-co-methacrylic acid) (PS-co-PMMA) microspheres as the sacrificial substrate, griseofulvin as the template, a photoresponsive azobenzene derivative 4-((4-(methacryloyloxy)phenyl)diazenyl)-3,5-dimethyl benzenesulfonic acid as the functional monomer, and triethanolamine trimethacrylate as the cross-linker. The PMIPS was obtained after the removal of the sacrificial PS-co-PMMA core from the surface imprinted core-shell microspheres, PS-co-PMAA@PMIP. Compared with PS-co-PMAA@PMIP, PMIPS displayed better properties such as higher surface area and pore volume, rapid photo-isomerization rate, and higher adsorption capacities, specific binding constant and binding density. The PMIPS could efficiently detect griseofulvin in complex samples such as milk. Copyright © 2018 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)365-373
JournalMaterials Science and Engineering: C
Volume92
Early online date02 Jul 2018
DOIs
Publication statusPublished - Nov 2018

Fingerprint

Griseofulvin
Polymers
Polymethyl Methacrylate
Microspheres
Photoisomerization
Styrene
Milk
Monomers
Derivatives
Adsorption
Substrates

Citation

Yang, Y.-H., Liu, L.-T., Chen, M.-J., Liu, S., Gong, C.-B., Wei, Y.-B., . . . Tang, Q. (2018). A photoresponsive surface molecularly imprinted polymer shell for determination of trace griseofulvin in milk. Materials Science and Engineering: C, 92, 365-373. doi: 10.1016/j.msec.2018.06.069

Keywords

  • Surface molecularly imprinted polymer
  • Griseofulvin
  • Photoresponsive materials
  • Milk
  • Poly(styrene-co-methacrylic acid) microspheres