A new photoresponsive surface molecularly imprinted polymer shell (PMIPS) was developed for determination of trace griseofulvin from milk. The PMIPS was prepared by surface imprinting technique using poly(styrene-co-methacrylic acid) (PS-co-PMMA) microspheres as the sacrificial substrate, griseofulvin as the template, a photoresponsive azobenzene derivative 4-((4-(methacryloyloxy)phenyl)diazenyl)-3,5-dimethyl benzenesulfonic acid as the functional monomer, and triethanolamine trimethacrylate as the cross-linker. The PMIPS was obtained after the removal of the sacrificial PS-co-PMMA core from the surface imprinted core-shell microspheres, PS-co-PMAA@PMIP. Compared with PS-co-PMAA@PMIP, PMIPS displayed better properties such as higher surface area and pore volume, rapid photo-isomerization rate, and higher adsorption capacities, specific binding constant and binding density. The PMIPS could efficiently detect griseofulvin in complex samples such as milk. Copyright © 2018 Elsevier B.V. All rights reserved.
CitationYang, Y.-H., Liu, L.-T., Chen, M.-J., Liu, S., Gong, C.-B., Wei, Y.-B., . . . Tang, Q. (2018). A photoresponsive surface molecularly imprinted polymer shell for determination of trace griseofulvin in milk. Materials Science and Engineering: C, 92, 365-373. doi: 10.1016/j.msec.2018.06.069
- Surface molecularly imprinted polymer
- Photoresponsive materials
- Poly(styrene-co-methacrylic acid) microspheres