乳腺癌患者相關症狀及其對生活品質的影響研究

馬玲, 王世平, 鍾慧儀

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Abstract

目的 瞭解乳腺癌患者相關症狀的發生情況及其對生活品質的影響。
方法 橫斷面調查設計,以記憶症狀評估量表和生活品質調查問卷(第3版)對四川大學華西醫院等3所醫院的200例乳腺癌患者進行面對面的問卷調查。
結果 乳腺癌各種症狀中發生率居前五位的有缺乏活力、脫髮、精神緊張、出汗和焦慮不安;出現頻率高居前五位元的症狀是缺乏活力、睡眠不好、口乾、沒有食慾和出汗;嚴重程度居前五位的症狀是脫髮、缺乏活力、睡眠不好、精神緊張和進食口味改變;對患者造成困擾程度居前五位的症狀是脫髮、感到“我看起來不像自己”、睡眠不好、沒有食欲和缺乏活力;對乳腺癌患者整體生活品質的影響從大到小依次為缺乏活力、焦慮不安、疼痛、睡眠不好、便秘、急躁易怒、口乾、出汗、手腳感到麻木或刺痛、皮膚改變、腹瀉、噁心、沒有食欲、氣緊或呼吸困難,確定係數R2=0.790。
結論  乳腺癌患者最突出的症狀是缺乏活力;脫髮是使患者感到最困擾的問題;其他值得注意的症狀有:感到“我看起來不像自己”,睡眠不好,沒有食慾。對患者整體生活品質評分產生影響的症狀有14項,它們可以共同解釋乳腺癌患者整體生活品質評分總變異的79.0%。
Objective To identify the correlative symptoms of breast cancer patients and their influence on quality of life.
Methods The cross-sectional study was used.A face-to-face survey was administered to 200 breast cancer patients, using two scales: ① Memorial Symptom Assessment Scale(MSA); ② European Organization for Research and Treatment of Cancer Core Quality-of-Life Questionnaire (Version 3) [EORTIC QLQ-C30].
Results The top five most highly prevalent symptoms were: lack of energy, hair loss, nervousness, sweating and worry. The five most frequent symptoms were: lack of energy, difficulty in sleeping, dry mouth, lack of appetite and sweating. The five most severe symptoms were: hair loss, lack of energy, difficulty in sleeping, nervousness and a change in food preference. The top fivesymptoms causing much distress were: hair loss, a feeling of “I don’t look like myself”, difficulty in sleeping, lack of appetite and lack of energy. The major factors influencing quality of life were: lack of energy, worry, pain, difficulty in sleeping, constipation, irritability, dry mouth, sweating, numbness/tingling in hands/feet, changes in skin, diarrhea, nausea, lack of appetite, and shortness of breath. Adjusted R square was 0.790.
Conclusions The most conspicuous symptom in breast cancer patients is lack of energy. The symptom that distresses patients most is hair loss. The other notable symptoms are: “I don’t look like myself”, difficulty in sleeping, and lack of appetite. In addition, the quality of life is influenced by fourteen symptoms, and these symptoms account for 79.0% of the variance in quality of life. Copyright © 2007 中國循證醫學雜誌編輯部.
Original languageChinese
Pages (from-to)169-174
Journal中國循證醫學雜誌
Volume7
Issue number3
Publication statusPublished - 2007

Citation

馬玲、王世平和鍾慧儀(2007):乳腺癌患者相關症狀及其對生活貭量的影響研究,《中國循證醫學雜誌》,7(3),頁169-174。

Keywords

  • 乳腺癌
  • 相關症狀
  • 生活品質
  • Breast cancer
  • Correlative symptoms
  • Quality of life